Hydrocodone/ibuprofen has a danger for abuse and addiction, which have the right to lead come overdose and death. Hydrocodone/ibuprofen may additionally cause severe, perhaps fatal, breath problems. To reduced your risk, your physician should have you take it the the smallest dose of hydrocodone/ibuprofen the works, and take it for the shortest feasible time. See also How to Use ar for much more information around addiction.

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The risk for significant breathing troubles is greater when you begin this medication and also after a dose increase, or if you take the not correct dose/strength. Acquisition this medication with alcohol or other drugs that can cause drowsiness or breathing problems may cause really serious side effects, including death. Also, other medications can affect the removed of hydrocodone/ibuprofen from your body, i m sorry may influence how hydrocodone/ibuprofen works. Be sure you know exactly how to take it hydrocodone/ibuprofen and what other drugs you should avoid taking v it. See additionally Drug interactions section. Get medical help right away if any type of of these really serious side results occur: slow/shallow breathing, inexplicable lightheadedness, serious drowsiness/dizziness, challenge waking up.

Keep this medicine in a safe location to avoid theft, misuse, or abuse. If someone accidentally swallows this drug, acquire medical help right away.

The other ingredient in this medication, ibuprofen, might rarely cause serious (rarely fatal) bleeding from the stomach or intestines. Also, nonsteroid anti-inflammatory medicine (including ibuprofen) may rarely boost the danger for a heart strike or stroke. This result can occur at any type of time while acquisition this drug however is more likely if you take it it because that a lengthy time. The risk might be higher in older adult or if you have actually heart disease or raised risk because that heart disease (for example, as result of smoking, family background of heart disease, or problems such as high blood pressure or diabetes). Carry out not take it this medicine right prior to or after love bypass surgery (CABG). Talk to your physician or pharmacist about the benefits and risks of treatment, and also other possible medication choices.

Stop taking this medication and also get medical assist right away if you notification any that the following rare but really serious next effects: chest pain, significant dizziness, weak on one next of the body, vision changes, problem speaking, black color stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds. (See likewise Precautions section.)

Before making use of this medication, females of childbearing period should talk through their doctor(s) about the benefits and also risks. Tell your doctor if you are pregnant or if you arrangement to come to be pregnant. This medicine may damage an unborn baby and also cause difficulties with regular labor/delivery. It is no recommended for usage in pregnant from 20 weeks until delivery. If your medical professional decides the you need to use this medication in between 20 and also 30 mainly of pregnancy, you have to use the lowest effective dose because that the shortest feasible time. You have to not usage this medication after 30 main of pregnancy. Babies born to mother who use this drug for a long time may develop severe (possibly fatal) tap the money symptoms. Phone call the doctor right away if you an alert any symptoms in her newborn baby such together crying the doesn"t stop, slow/shallow breathing, irritability, shaking, vomiting, diarrhea, negative feeding, or challenge gaining weight.

Read the medication Guide noted by your pharmacist before you start using this medication and also each time you obtain a refill. If you have any type of questions, asking your doctor or pharmacist.

Take this medication by mouth as directed by her doctor, usually every 4 come 6 hrs as needed. Take it through a complete glass the water (8 ounces or 240 milliliters) uneven your physician directs girlfriend otherwise. Execute not lie under for at the very least 10 minutes after taking this drug. You might take this drug through or there is no food. If you have nausea, that may aid to take it this drug with food. Asking your physician or pharmacist around other ways to to decrease nausea (such together lying down for 1 come 2 hrs with as small head motion as possible).

The dosage is based on your medical problem and solution to treatment. To reduce your hazard of stomach bleeding and also other side effects, take this medication at the lowest effective dose because that the shortest feasible time. Perform not rise your dose, take it the medication more frequently, or take it because that a longer time than prescribed. Properly stop the medication once so directed. The manufacturer recommends you take it no more than 5 tablet computers in a 24-hour period.

Pain drugs work ideal if lock are provided as the first signs of pain occur. If friend wait until the pain has worsened, the medication might not job-related as well. Also follow her doctor"s or pharmacist"s directions because that the safe use of other non-opioid ache relievers (such together acetaminophen).

Suddenly stopping this medication may cause withdrawal, particularly if you have used it for a lengthy time or in high doses. To prevent withdrawal, your physician may reduced your dose slowly. Phone call your doctor or pharmacist ideal away if girlfriend have any type of withdrawal symptoms such together restlessness, mental/mood alters (including anxiety, trouble sleeping, thoughts of suicide), watering eyes, runny nose, nausea, diarrhea, sweating, muscle aches, or sudden alters in behavior.

When this medicine is provided for a long time, it might not work as well. Talk with your doctor if this medication falls short well.

Though the helps countless people, this medication may sometimes reason addiction. This risk may be higher if you have a substance use disorder (such together overuse that or addiction to drugs/alcohol). Take this medication specifically as prescribed to lower the threat of addiction. Asking your physician or pharmacist for much more details.

Tell your physician if her pain does no get far better or if it it s okay worse.
See additionally Warning section.

Upset stomach, nausea, vomiting, constipation, dizziness, lightheadedness, or drowsiness may occur. If any kind of of these results persist or worsen, call your physician or pharmacist promptly.

To avoid constipation, eat diet fiber, drink sufficient water, and also exercise. Girlfriend may likewise need to take a laxative. Ask your pharmacist which form of laxative is ideal for you.

To reduce the risk of dizziness and lightheadedness, gain up slowly when increasing from a sitting or lying position.

Remember the your doctor has prescribed this medication because he or she has judged the the advantage to you is greater than the hazard of next effects. Many people using this medication perform not have actually serious side effects.

Tell your medical professional right far if you have any type of serious next effects, including: easy bruising/bleeding, fast/pounding heartbeat, difficult/painful swallowing, interrupted breathing throughout sleep (sleep apnea), mental/mood alters (such together agitation, confusion, hallucinations), challenge urinating, unusual weakness, indicators of your adrenal glands not working well (such as loss that appetite, inexplicable tiredness, weight loss), symptom of heart failure (such together swelling ankles/feet, unusual/sudden weight gain).

Stop taking this medication and get medical assist right far if any of these really serious side results occur: fainting, slow/irregular/shallow breathing, indicators of kidney problems (such as adjust in the quantity of urine), major drowsiness/difficulty waking up, unusual fever, persistent/severe headache, unexplained stiff neck, seizure.

This drug might rarely reason serious, maybe fatal, liver disease. Stop taking this medication and get medical assist right away if girlfriend have any symptoms of liver damage, including: dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin.

A very serious allergy reaction to this drug is rare. However, obtain medical assist right far if you notification any symptoms of a major allergic reaction, including: fever, swollen lymph nodes, rash/blisters, itching/swelling (especially of the face/tongue/throat), major dizziness, problem breathing.

This is not a complete list of possible side effects. If you notification other results not listed above, contact your medical professional or pharmacist.

In the us -

Call your medical professional for clinical advice around side effects. You may report side effects to FDA in ~ 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - contact your medical professional for medical advice around side effects. You might report side impacts to wellness Canada in ~ 1-866-234-2345.
Before taking this medication, tell your doctor or pharmacist if you are allergic to ibuprofen or hydrocodone; or to aspirin or other NSAIDs (such as naproxen, celecoxib); or to various other opioids (such as benzhydrocodone, codeine, morphine, hydromorphone); or if you have any kind of other allergies. This product might contain inactive ingredients, which can cause allergic reaction or various other problems. Speak to your pharmacist for more details.

Before utilizing this medication, phone call your doctor or pharmacist your clinical history, particularly of: aspirin-sensitive asthma (a background of worsening breathing through runny/stuffy sleep after taking aspirin or various other NSAIDs), low red blood cell counting (anemia), bleeding or coagulation problem, mind disorders (such as head injury, tumor, seizures, stroke), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), growths in the nose (nasal polyps), high blood pressure, heart problems (such as irregular heartbeat, recent heart attack), liver disease, mental/mood disorders (such as confusion, depression, think of suicide), an individual or family history of a substance usage disorder (such together overuse the or addiction to drugs/alcohol), stomach/intestinal problems (such together ulcer, blockage, constipation, diarrhea due to infection, paralytic ileus), fluid retention/swelling the the ankles/feet/hands, an obstacle urinating (such as because of enlarged prostate), gallbladder disease, condition of the pancreas (pancreatitis).

Kidney difficulties can sometimes happen with the use of NSAID medications, consisting of ibuprofen. Problems are much more likely to happen if you are dehydrated, have heart failure or kidney disease, space an enlarge adult, or if friend take details medications (see additionally Drug interactions section). Drink many of fluids together directed by your doctor to prevent dehydration and also tell your medical professional right far if you have a readjust in the quantity of urine.

This drug may make girlfriend dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Carry out not drive, usage machinery, or carry out anything that demands alertness till you deserve to do it safely. Protect against alcoholic beverages. Talk to your doctor if you room using marijuana (cannabis).

Before having surgery, call your medical professional or dentist about all the products you usage (including prescription drugs, nonprescription drugs, and also herbal products).

This medication may reason stomach bleeding. Daily use the alcohol and also tobacco, specifically when an unified with this medicine, may rise your danger for stomach bleeding. Avoid alcohol and stop smoking. Above your physician or pharmacist for much more information.

Older adults might be at greater risk for dizziness, drowsiness, confusion, stomach/intestinal bleeding, kidney problems, heart attack, stroke, and also slow/shallow breathing while making use of this drug.

Children may be more sensitive to the side results of this drug, especially slow/shallow breathing.

During pregnancy, this medication must be offered only when clearly needed. That may injury an unborn baby. Comment on the risks and also benefits v your doctor. (See likewise Warning section.)

This drug passes right into breast milk and may have actually undesirable results on a education infant. Phone call the doctor right far if your baby establishes unusual sleepiness, an obstacle feeding, or problem breathing. Consult your doctor before breast-feeding.
See additionally Warning section.

Drug interactions may readjust how your medicines work or boost your threat for significant side effects. This paper does no contain all feasible drug interactions. Keep a perform of all the products you use (including prescription/nonprescription drugs and also herbal products) and share it through your doctor and pharmacist. Carry out not start, stop, or readjust the dosage of any type of medicines without your doctor"s approval.

Some assets that may interact with this drug include: aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as valsartan, losartan), corticosteroids (such together prednisone), lithium, naltrexone, pemetrexed, probenecid, particular pain drugs (mixed opioid agonist-antagonists such together pentazocine, nalbuphine, butorphanol).

This medicine may boost the risk of bleeding as soon as taken with various other drugs that also may reason bleeding. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, amongst others.

Other medications can affect the removal of hydrocodone/ibuprofen from your body, i m sorry may influence how hydrocodone/ibuprofen works. Examples incorporate azole antifungals (such as ketoconazole), macrolide antibiotics (such together erythromycin), mifepristone, HIV medications (such as ritonavir), rifamycins (such as rifabutin, rifampin), specific drugs used to treat seizures (such together carbamazepine, phenytoin), among others.

Check all prescription and also nonprescription medication labels carefully for ibufrofen or other pain/fever medicine (aspirin, NSAIDs such as celecoxib, ketorolac, or naproxen). This drugs are comparable to ibuprofen, therefore taking one of these medicine while likewise taking ibufrofen may rise your danger of next effects. However, if your doctor has directed friend to take low-dose aspirin for heart assault or stroke prevention (usually 81-162 milligrams a day), you should continue taking the aspirin uneven your medical professional instructs girlfriend otherwise.

Daily usage of ibuprofen might decrease aspirin"s ability to avoid heart attack/stroke. Talk to your doctor around using a various medication (such together acetaminophen) to treat pain. If you must take ibuprofen, speak to her doctor around taking immediate-release aspirin (not enteric-coated/EC) while acquisition ibuprofen. Take this product at least 8 hours before or at the very least 2 hrs after her aspirin dose. Perform not boost your daily dose the aspirin or change the method you take aspirin/other medicines without her doctor"s approval.

The danger of significant side results (such together slow/shallow breathing, serious drowsiness/dizziness) might be increased if this medication is taken through other commodities that may likewise cause drowsiness or breath problems. Phone call your medical professional or pharmacist if you are taking other products such as various other opioid pain or cough relievers (such as codeine, oxycodone), alcohol, marijuana (cannabis), drugs for sleep or stress and anxiety (such together alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such together cetirizine, diphenhydramine).

Check the labels on all your medications (such as allergy or cough-and-cold products) since they may contain ingredients that reason drowsiness. Ask your pharmacist around using those products safely.

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This medication may interfere with specific laboratory tests (including amylase/lipase levels), possibly bring about false test results. Make sure laboratory personnel and all your doctors know you usage this drug.